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What is the difference between Pre-implantation Genetic Diagnosis (PGD) and Pre-Implantation Screening (PGS)?
These are both pre-implantation genetics tests (PGT) done on the embryo before embryo transfer. The embryos are obtained through a process called in-vitro fertilisation (IVF).
| PGS | PGD | |
| Testing for normal chromosome numbers (23 pairs) | What it involves | Test for specific, known genetic disorder |
| 1 or more cells are taken from embryo while it is still in the lab | How it is done | 1 or more cells are taken from embryo while it is still in the lab |
| To increase IVF success and reduce miscarriages | What its purpose is | To reduce risk of passing on the specific genetic disorder |
| Couples with recurrent miscarriage, low quality eggs, multiple failed IVF cycles | Who it is recommended for | 1 or both parent are carriers of known genetic disorder |
Depending on the country, PGD and PGS are governed by different rules and regulations. You should discuss with your gynaecologist to see if you are suitable for, or require pre-implantation genetic tests.
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